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The Dr. Madeira Show

64 conversations with doctors, researchers and practitioners on environmental medicine, brain health, hormones, herbal medicine and men’s health, hosted by Dr. Sam Madeira, NMD.

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Environmental medicine & mold

Mold, mycotoxins, hidden infections and everyday chemicals, and how they affect hormones and the brain.

Episode 55 · 65 min · May 2020

Mold illness and brain health

with Dr. Lauren Tessier

How serious mold illness can be, and how it affects the brain.

Show notes & key takeaways

In this episode

  • Why mold-related illness can be serious and easy to miss
  • How mold exposure can affect the brain, mood and thinking
  • Preventing mold problems at home

Key takeaways

  1. Mold-related illness can affect the brain as well as the body, and it’s easy to overlook when symptoms look like stress or aging.
  2. Dr. Tessier explains why people with ongoing brain fog, mood changes or fatigue may want their indoor environment considered.
  3. Prevention matters: fixing moisture problems early is far simpler than dealing with mold later.

About the guest

Dr. Lauren Tessier is a licensed naturopathic physician who focuses on mold-related illness and has served as vice president of the International Society for Environmentally Acquired Illness (ISEAI).

Learn more about this topic: Mold illness → · Also on Apple Podcasts

Episode 37 · 69 min · January 2020

How mold mycotoxins affect your thyroid and sex hormones

with Dr. Jill Crista, ND

The mechanisms by which mycotoxins can lower thyroid and gonadal hormone function.

Show notes & key takeaways

In this episode

  • Why mold illness is driven more by toxins (mycotoxins) than by spores
  • How mycotoxins may affect mitochondria, the immune system and protein production
  • Research on mycotoxins and thyroid and sex-hormone function
  • Why people with ongoing fatigue and brain fog may want their home environment assessed

Key takeaways

  1. Mold illness is driven more by the toxins mold makes (mycotoxins) than by the spores themselves.
  2. Dr. Crista describes research suggesting some mycotoxins can affect energy production in cells, immune function, and thyroid and sex hormones.
  3. People with persistent fatigue and brain fog may benefit from having both their home and their health assessed for mold.

About the guest

Dr. Jill Crista is a naturopathic doctor, author of Break the Mold, and an educator on mold-related health issues.

Learn more about this topic: Mold illness → · Also on Apple Podcasts

Episode 25 · 61 min · October 2019

How to tell if toxic mold is in your home

with Brian Karr

Finding and removing mold for people who are mold-sensitive, and why it matters for hormone health.

Show notes & key takeaways

In this episode

  • How water damage leads to mold and bacterial toxins indoors, in any climate
  • Working with an expert team to find and remove mold for people who are sensitive to it
  • Why some people react more strongly to mold than others
  • Links between indoor mold and fatigue, brain fog and hormone problems

Key takeaways

  1. Any home with past water damage, in any climate, can harbor mold and bacterial toxins.
  2. Brian Karr explains why mold-sensitive people often need a careful, expert approach to finding and removing mold.
  3. Some people are more sensitive to mold than others, so one person in a home can be affected while others aren’t.

About the guest

Brian Karr works in indoor environmental assessment and mold remediation for mold-sensitive clients.

Learn more about this topic: Free mold & toxin checklist → · Also on Apple Podcasts

Episode 41 · 118 min · February 2020

Environmental toxins and your hormone health

with Lara Adler

How environmental toxins affect hormones, brain health and fertility, and practical ways to reduce exposure.

Show notes & key takeaways

In this episode

  • Everyday chemical exposures and their effects on hormones, the brain and fertility
  • Endocrine disruptors and how they act in the body
  • Practical ways to reduce your exposure at home

Key takeaways

  1. Many everyday products contain chemicals that can act on hormones (endocrine disruptors).
  2. Lara Adler explains how these exposures may affect hormones, brain health and fertility.
  3. Practical swaps at home can reduce your exposure without turning your life upside down.

About the guest

Lara Adler is an environmental toxins educator and certified holistic health coach who trains health practitioners on everyday toxic exposures.

Learn more about this topic: Environmental medicine → · Also on Apple Podcasts

Episode 64 · 95 min · March 2021

Estrogeneration: plastics, fake estrogens and low hormones

with Dr. Anthony Jay, PhD

Plastic toxicity and estrogen-mimicking chemicals, and their links to low hormones and infertility.

Show notes & key takeaways

In this episode

  • His book Estrogeneration and estrogen-mimicking chemicals
  • Plastic exposure and its links to hormone disruption
  • Falling testosterone levels in adult men
  • Cholesterol, heart health and brain health

Key takeaways

  1. Dr. Jay discusses his book Estrogeneration and chemicals that mimic estrogen in the body.
  2. Plastics are a common, everyday source of these estrogen-like chemicals.
  3. The conversation explores possible links between these exposures, falling testosterone levels and fertility.

About the guest

Dr. Anthony Jay, PhD is a research scientist and the author of Estrogeneration.

Learn more about this topic: Low testosterone → · Also on Apple Podcasts

Episode 18 · 61 min · September 2019

Stealth infections: EBV, Lyme and mold

with Dr. Kasey Holland, ND

How hidden infections and mold can disrupt hormones and drive chronic symptoms.

Show notes & key takeaways

In this episode

  • What “stealth” infections such as Epstein–Barr virus and Lyme disease are
  • How hidden infections and mold can contribute to fatigue, brain fog and hormone changes
  • Why testing with an experienced clinician matters when looking for root causes

Key takeaways

  1. “Stealth” infections such as Epstein–Barr virus and Lyme disease can be hard to detect.
  2. Dr. Holland explains how hidden infections and mold may contribute to fatigue, brain fog and hormone changes.
  3. Testing with a clinician experienced in these conditions helps look for root causes rather than just symptoms.

About the guest

Dr. Kasey Holland is a naturopathic doctor.

Learn more about this topic: Long COVID & ME/CFS → · Also on Apple Podcasts

Brain health & concussion recovery

Traumatic brain injury, concussion and protecting the brain over a lifetime.

Episode 63 · 83 min · March 2021

Concussion recovery tips

with Dr. Mark Heisig

A naturopathic doctor and functional neurologist on how common concussion is and how to support healing.

Show notes & key takeaways

In this episode

  • How common concussion and mild traumatic brain injury are
  • Physical, cognitive and emotional symptoms of concussion
  • Why feeling better is not always the same as full recovery of brain metabolism
  • Possible drivers of post-concussion syndrome
  • Supporting recovery with nutrition, movement and mindset, including by telemedicine

Key takeaways

  1. Concussion and mild traumatic brain injury are more common than most people realize.
  2. Dr. Heisig explains that feeling better doesn’t always mean the brain has fully recovered.
  3. Nutrition, movement and mindset are central to recovery, and much of that support can happen by telemedicine.

About the guest

Dr. Mark Heisig is a naturopathic doctor who focuses on integrative neurology and concussion recovery.

Learn more about this topic: Brain fog & concussion → · Also on Apple Podcasts

Episode 46 · 58 min · March 2020

Concussion Rescue

with Dr. Kabran Chapek, ND

His book on concussion recovery and his clinical work with brain injuries.

Show notes & key takeaways

In this episode

  • His book Concussion Rescue
  • Differences in concussion risk and recovery between men and women
  • Brain imaging approaches and what they can show
  • Natural medicine approaches to concussion and post-concussion syndrome

Key takeaways

  1. Dr. Chapek discusses his book Concussion Rescue and his work with people recovering from brain injuries.
  2. Concussion risk and recovery can differ between men and women.
  3. Natural medicine approaches can be part of a broader recovery plan after a concussion.

About the guest

Dr. Kabran Chapek is a naturopathic doctor, a Bastyr University graduate, and the author of Concussion Rescue.

Learn more about this topic: Brain fog & concussion → · Also on Apple Podcasts

Episode 42 · 87 min · February 2020

A TBI case study

with Dr. Paul Anderson, NMD

Dr. Anderson reviews a case study of Dr. Madeira’s own recovery after an acute head injury.

Show notes & key takeaways

In this episode

  • Dr. Madeira’s own head injury after he was rear-ended in 2018
  • The treatment course Dr. Anderson used and presented to physicians as a case study
  • Dr. Madeira’s personal experience of recovery

Key takeaways

  1. Dr. Madeira shares his own experience of recovering from a head injury after a car accident in 2018.
  2. Dr. Anderson describes the treatment course he presented to physicians as a case study.
  3. The episode describes in-office therapies that Apollo Health Clinic doesn’t offer; care at Apollo is 100% telemedicine.

This episode describes in-office therapies (hyperbaric oxygen and IV nutrients) that Apollo Health Clinic does not provide. Care at Apollo is 100% telemedicine.

About the guest

Dr. Paul Anderson, NMD is a naturopathic physician, co-author of Outside the Box Cancer Therapies, and a teacher in continuing medical education.

Learn more about this topic: Brain fog & concussion → · Also on Apple Podcasts

Episode 54 · 56 min · May 2020

Brain health and preventing neurodegeneration

with Dr. Greg Eckel

An integrative look at protecting the brain, and his book on Parkinson’s disease.

Show notes & key takeaways

In this episode

  • Integrative approaches to protecting the brain over time
  • His book on Parkinson’s disease, Shake It Off
  • What his wife’s illness taught him about neurological disease

Key takeaways

  1. Protecting the brain over a lifetime is possible to think about long before problems appear.
  2. Dr. Eckel discusses his integrative approach and his book on Parkinson’s disease, Shake It Off.
  3. He shares what his wife’s illness taught him about neurological disease and caregiving.

About the guest

Dr. Greg Eckel is a naturopathic doctor and acupuncturist and the author of Shake It Off: An Integrative Approach to Parkinson’s Solutions.

Learn more about this topic: Brain fog & concussion → · Also on Apple Podcasts

Hormones & men’s health

Testosterone, thyroid, sleep and the overlooked drivers of hormone imbalance.

Episode 6 · 51 min · June 2019

The overlooked causes of low testosterone

Dr. Madeira reviews the most commonly missed causes of low testosterone in men.

Show notes & key takeaways

In this episode

  • Chronic stress and inflammation
  • Poor sleep
  • Stealth infections
  • Nutrient deficiencies, and dietary fats and cholesterol
  • Medications
  • Excess weight and blood sugar problems, including prediabetes

Key takeaways

  1. Low testosterone often has underlying contributors that are worth looking for before considering treatment.
  2. Dr. Madeira walks through commonly overlooked causes: chronic stress, inflammation, poor sleep, stealth infections and nutrient gaps.
  3. Medications, excess weight and blood sugar problems can also play a part.

Learn more about this topic: Low testosterone → · Also on Apple Podcasts

Episode 5 · 35 min · June 2019

Myths of testosterone and testosterone therapy

Five common myths about testosterone, and what the evidence actually shows.

Show notes & key takeaways

In this episode

  • Whether low testosterone only affects men over 50
  • Whether herbs alone can raise testosterone enough in men with a true deficiency
  • Whether fatigue is only an adrenal or thyroid issue
  • What the research says about testosterone therapy and prostate cancer
  • Why building blocks such as cholesterol and pregnenolone aren’t the whole story

Key takeaways

  1. Low testosterone isn’t only a concern for men over 50.
  2. Dr. Madeira looks at common beliefs about testosterone and what the research says about each.
  3. Whether any treatment is appropriate depends on an individual assessment and on federal and state rules.

Recorded in 2019 as general education. Whether testosterone therapy is appropriate depends on an individual assessment and on federal and state rules.

Learn more about this topic: Low testosterone → · Also on Apple Podcasts

Episode 36 · 63 min · January 2020

Men’s hormones and health span

with Dr. Ralph Esposito, ND, L.Ac.

Testosterone, thyroid hormone and how they shape long-term health.

Show notes & key takeaways

In this episode

  • Supporting healthy testosterone levels
  • How thyroid hormone affects androgen receptors
  • The link between cortisol balance and hormone health
  • Which lab tests can give a fuller picture of hormone health

Key takeaways

  1. Testosterone, thyroid hormone and cortisol work together, so looking at one alone can miss the bigger picture.
  2. Dr. Esposito explains how thyroid hormone affects how the body responds to androgens.
  3. Targeted lab testing can give a fuller picture of men’s hormone health.

About the guest

Dr. Ralph Esposito is a naturopathic physician and licensed acupuncturist who focuses on integrative urology, endocrinology and men’s health.

Learn more about this topic: Low testosterone → · Also on Apple Podcasts

Episode 26 · 57 min · October 2019

Comprehensive hormone testing

with Dr. Carrie Jones, ND, MPH

Lab testing for men’s hormones, and approaches beyond testosterone alone.

Show notes & key takeaways

In this episode

  • Testing thyroid, adrenal hormones, testosterone and estrogen in men
  • Leptin and leptin resistance
  • Lifestyle and natural approaches to hormone balance, including circadian rhythm

Key takeaways

  1. Comprehensive hormone testing for men can include thyroid, adrenal hormones, testosterone and estrogen.
  2. Dr. Jones explains leptin and leptin resistance, and why they matter for hormones and metabolism.
  3. Daily rhythms, such as sleep timing and light exposure, influence hormone balance.

About the guest

Dr. Carrie Jones, ND, MPH is a naturopathic doctor who specializes in hormones and has served as a medical director at Precision Analytical (the DUTCH test lab).

Learn more about this topic: Low testosterone → · Also on Apple Podcasts

Episode 34 · 111 min · January 2020

Sleep science and hormone health

with Dr. Kirk Parsley, MD

Why sleep is foundational for hormone health in men and women.

Show notes & key takeaways

In this episode

  • Why sleep is foundational for hormone health in men and women
  • His work on sleep with Navy SEALs
  • How to track your sleep
  • Why much of the body’s androgen production happens during sleep

Key takeaways

  1. Sleep is one of the foundations of hormone health for both men and women.
  2. Dr. Parsley shares lessons from his work on sleep with Navy SEALs.
  3. Much of the body’s androgen production happens during sleep, so poor sleep can affect hormones.

About the guest

Dr. Kirk Parsley, MD is a former Navy SEAL and physician who consults on sleep and performance.

Learn more about this topic: Low testosterone → · Also on Apple Podcasts

Herbal medicine & stress

Botanical medicine, the stress response and resilience.

Episode 28 · 65 min · November 2019

Berberine, ashwagandha and botanical medicine

with Professor Kerry Bone

The research behind berberine for longevity, ashwagandha for strength, and botanical medicine.

Show notes & key takeaways

In this episode

  • Research on berberine and how it compares with metformin in studies of aging
  • Research on ashwagandha and muscle strength
  • How some herbs act on cellular energy pathways (AMPK and mTOR)
  • Quality control problems in the herbal supplement market

Key takeaways

  1. Professor Bone reviews research on berberine and on ashwagandha.
  2. He explains how some herbs act on the body’s cellular energy pathways.
  3. Quality varies widely in the herbal supplement market, so sourcing and quality control matter.

About the guest

Professor Kerry Bone is an herbal medicine researcher, author of around 40 scientific papers on herbal research, and co-founder of MediHerb.

Learn more about this topic: How care works → · Also on Apple Podcasts

Episode 24 · 84 min · October 2019

The science of botanical medicines for metabolic health

with Lee Carroll, BSc, BHSc

How herbal medicines work for metabolic syndrome and low hormones in men.

Show notes & key takeaways

In this episode

  • What drives metabolic syndrome and insulin resistance
  • How metabolic health relates to low testosterone in men
  • The research on key botanical medicines and how they work

Key takeaways

  1. Metabolic syndrome and insulin resistance are closely linked to energy, weight and hormone health.
  2. Lee Carroll explains how metabolic health relates to low testosterone in men.
  3. He reviews the research behind several botanical medicines and how they’re thought to work.

About the guest

Lee Carroll, BSc, BHSc is a clinical herbalist.

Learn more about this topic: Low testosterone → · Also on Apple Podcasts

Episode 4 · 55 min · June 2019

What is the HPA axis? How chronic stress affects you

How chronic stress affects the body, and how to recognize it.

Show notes & key takeaways

In this episode

  • What the HPA (hypothalamic–pituitary–adrenal) axis is
  • Common signs of chronic stress, such as poor sleep, anxiety, weight gain and low thyroid function
  • How chronic stress relates to many common chronic conditions
  • Ways to make your stress response work for you

Key takeaways

  1. The HPA axis is the body’s main stress-response system, linking the brain and the adrenal glands.
  2. Long-term stress can show up as poor sleep, anxiety, weight gain, low thyroid function and more.
  3. Dr. Madeira shares ways to recognize chronic stress and support a healthier stress response.

Learn more about this topic: How care works → · Also on Apple Podcasts

Episode 11 · 17 min · August 2019

Prioritizing your health: herbs for sleep and chronic stress

Checking in with yourself, and herbal support for sleep and stress.

Show notes & key takeaways

In this episode

  • Checking whether your daily actions match your health priorities
  • Herbal medicines traditionally used for sleep
  • The chemistry and pharmacology behind them

Key takeaways

  1. A simple check-in helps you see whether your daily actions match your health priorities.
  2. Dr. Madeira discusses herbal medicines traditionally used to support sleep.
  3. Understanding how these herbs work helps you use them thoughtfully, ideally with professional guidance.

Learn more about this topic: How care works → · Also on Apple Podcasts

Episode 48 · 109 min · April 2020

Creating inner safety with mind-body practices

with Dr. Brad Lichtenstein, ND

Retraining the nervous system toward rest and balance during uncertain times.

Show notes & key takeaways

In this episode

  • Retraining the nervous system toward rest and calm
  • Meditation, mindfulness, compassion and breathwork
  • Biofeedback and heart rate variability wearables
  • Coping during times of uncertainty

Key takeaways

  1. The nervous system can be retrained toward rest and calm with regular practice.
  2. Dr. Lichtenstein explains meditation, mindfulness, compassion practices and breathwork.
  3. Biofeedback and heart rate variability tracking can show how your body responds to stress.

About the guest

Dr. Brad Lichtenstein is a naturopathic doctor, board certified in biofeedback, and a professor at Bastyr University who teaches mind-body medicine.

Learn more about this topic: How care works → · Also on Apple Podcasts

More from Dr. Madeira

Dr. Madeira has also been a guest on more than 20 other podcasts since 2018.

Podcast episodes are educational conversations and reflect the views of the speakers at the time they were recorded. They are not individual medical advice.

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